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Total vitamin D intake and predictors of circulating 25(OH)D in african american men
Author(s) -
AgursCollins Tanya,
Dodd Kevin,
Williams Erica,
Kittles Rick
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.lb209
Subject(s) - medicine , vitamin d and neurology , vitamin , african american , food frequency questionnaire , physiology , endocrinology , gastroenterology , history , ethnology
Purpose Evidence suggests that low vitamin D status is associated with chronic disease including colorectal cancer risk and all‐cause mortality. The purpose of this study was to assess vitamin D status against the new Institute of Medicine (IOM) vitamin D recommendation and to identify predictors of circulating 25(OH)D in 287 healthy African American men. Methods Total vitamin D intake and lifetime ultraviolet light (UV) exposure were measured by questionnaires. Circulating 25(OH)D was measured using serum. Descriptive statistics and linear regression models were used to assess vitamin D intake and explore predictors of circulating 25(OH)D. Results Mean total vitamin D intake (food and supplement) was 272.3 IUs/day (95% CI:245.0,299.6), with only 10% of the sample meeting the 600 IUs recommendation. Mean circulating 25(OH)D was 18.0 ng/ml (95% CI:17.0,19.1), with 35% of the sample who met the recommended 20 ng/ml. A significant predictor of 25(OH)D was total vitamin D intake (food and supplement) p<0.001; lifetime UV exposure was suggestive (p=0.08). We estimated that an increase of 200 IUs from total vitamin D (food and supplement) would increase circulating levels of 25(OH)D by 1.4 ng/ml. Conclusions When compared to the IOM recommendation, circulating vitamin D and intakes were inadequate, which may partially explain increased cancer risk and mortality among African American men.