Premium
Post‐exercise ingestion of a high protein diet does not enhance exercise‐induced skeletal muscle hypertrophy in rats
Author(s) -
Matsui Tomotsugu,
Yokota Yukari,
Kondo Emi,
Okamura Koji
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.983.4
Subject(s) - medicine , endocrinology , postprandial , muscle hypertrophy , ingestion , meal , skeletal muscle , physical exercise , myostatin , chemistry , insulin
A large protein intake increases both postprandial protein synthesis and post‐absorptive proteolysis. A high protein diet tended to reduce muscle growth, while ingesting the diet right after exercise alleviated the reduced muscle growth. However, muscle growth was not enhanced compared to a normal protein diet in rats (Kondo E. EB2008). We hypothesized that a high protein diet taken only after exercise might be effective for increasing the skeletal muscle mass. Rats were divided into 4 groups according to diet and exercise: a normal protein diet (N, 18% of energy) with sedentary conditions (NS), N with exercise (NE), a high protein diet (H, 35%) with sedentary conditions (HS) or H with exercise (HE). The rats in NE and HE exercised with a climbing cage from 19:00 to 20:00 (5 min × 6 sets/d, 3 d/w). All rats were fed N at 8:00–9:00 and 20:00–21:00, except for the 20:00–21:00 meal on the exercise days for HS and HE, when the rats were fed H. After 4 weeks, exercise increased the masses of the flexor hallucis longus muscle (FHL) and the sum of forearm flexor muscles (FAM) (P < 0.05), whereas no effect of diet was observed for these muscles. After 8 weeks, an exercise effect was observed in the masses of the FHL and FAM (E > S, P < 0.05), while no effect in regard to the diet was observed. Therefore, a high protein diet even ingested only after exercise does not appear to enhance exercise‐induced skeletal muscle hypertrophy in rats.