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Metabolic Syndrome and C ‐ reactive protein Levels among Mexican American Adults: Findings from the National Health and Nutrition Examination Surveys, 1999–2006
Author(s) -
Sarafrazi Neda,
Jackson Robert T,
Momen Bahram
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.982.9
Subject(s) - national health and nutrition examination survey , medicine , quartile , metabolic syndrome , confounding , odds ratio , c reactive protein , logistic regression , diabetes mellitus , obesity , environmental health , gerontology , demography , endocrinology , inflammation , confidence interval , population , sociology
Several studies have found associations between low grade inflammation and metabolic syndrome (MetS) risk factors, cardiovascular disease (CVD) and diabetes mellitus. Little information is available on C‐reactive protein (CRP) distribution and its relation with MetS in Mexican Americans (MA). We investigated the association between CRP and MetS in MA adults. We also compared the odds ratios (ORs) of developing MetS or its components according to quartiles of CRP. Data from 3265 MA adults who participated in the National Health and Nutrition Examination Survey 1999–2006, were used. Regression analysis was addressed the associations between log transformed CRP with the components of MetS after adjusting for the relevant confounders. Logistic regression was used to estimate the odds ratios of developing MetS according to quartile of CRP after controlling for confounders. Significant associations were observed between CRP and MetS components. In multiple logistic regression analysis with age, gender, drinking, smoking, marital status, medication use, arthritis and all the components of MetS, only central obesity and gender were significant predictors of elevated CRP concentration. Mexican Americans with MetS and low grade inflammation might be at higher risk for developing CVD and diabetes. Appropriate approaches for prevention, treatment and management of MetS and/or chronic inflammation are needed. Grant Funding Source : N/A