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A pilot study of diet and colorectal polyps by race
Author(s) -
Steck Susan E.,
Burch James B.,
Hurley Tom,
Cavicchia Philip,
Alexander Melannie,
Shivappa Nitin,
Hebert James R.
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.978.3
Subject(s) - medicine , colonoscopy , colorectal cancer , etiology , incidence (geometry) , race (biology) , gastroenterology , demography , cancer , physics , botany , sociology , optics , biology
Racial differences in colorectal cancer incidence and mortality exist, with African Americans (AAs) carrying an unequal burden of disease. A pilot study among AAs (n=42) and European Americans (EAs, n=94) in South Carolina was conducted to examine racial differences in colorectal polyps and lifestyle factors that may be important in polyp etiology. Participants undergoing colonoscopy were recruited from a local endoscopy center and completed dietary screeners and demographic questionnaires. Medical record abstraction was performed to obtain clinical data. Means and frequencies of clinical data, demographic factors, and dietary factors were compared between races and polyp status using t‐tests and chi‐square tests. A higher percentage of AAs had 2 or more polyps removed (56%) compared with EAs (41%). Mean intake of fruits and vegetables was similar between races (AA=2.7 ± 2.6 servings/d, EAs=2.1 ± 1.7 servings/d), as was percent energy from fat (AA=32.3 ± 3.0%, EA=31.9 ± 3.6%). Fruit and vegetable servings and percent energy from fat did not differ between those with multiple polyps vs. those with one or no polyps. In this pilot study, dietary factors showed little evidence for explaining racial differences in number of polyps detected. Future work will examine other clinical parameters of polyps in relation to diet and lifestyle factors by race. Grant Sponsor: SCCDCN U01 CA114601.