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Post‐Liver Transplant Weight Gain and its Effect on Cardiovascular Disease Risk Factors
Author(s) -
Stogsdill Gracen,
Gonzales Dana,
Hays Nicholas,
Hakkak Reza
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.971.39
Subject(s) - overweight , medicine , dyslipidemia , blood pressure , obesity , lipid profile , liver disease , weight gain , risk factor , population , liver transplantation , gastroenterology , cholesterol , transplantation , environmental health , body weight
Objective To determine if post liver transplant weight gain results in increased cardiovascular disease risk by increasing risk factors such as blood pressure and lipid levels after transplant. Methods Data on 69 patients who received a liver transplant from 2006–2008 at the University of Arkansas for Medical Sciences Liver Transplant Program was collected by electronic medical record review. Descriptive statistics were calculated to describe differences between groups. BMI, blood pressure and lipid levels were evaluated to examine a correlation between the groups. Results Overweight and obesity were common after liver transplant with 72% of the population overweight or obese at 1 year post transplant and 75.6% overweight or obese at the most recent time point analyzed. Blood pressure, total cholesterol, LDL and triglycerides all increased after transplant, while HDL‐cholesterol decreased. A significant relationship exists between blood pressure, HDL‐cholesterol and BMI after liver transplant. Conclusion Increase in blood pressure, lipid levels, BMI and overweight/obesity after liver transplant is common. Pre‐transplant patient education on the risk of weight gain, overweight and obesity, HTN, and dyslipidemia after transplant as well as ongoing follow up post transplant for weight management is warranted. Supported by: Department of Dietetics and Nutrition.