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Effects of lifestyle intervention on blood pressure and serum leptin in high blood pressure Korean men
Author(s) -
Kim EunJin,
Cho SangWoon,
Hwang MyungOk,
Paek YunMi,
Choi TeaIn,
Park YooKyoung
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.971.3
Subject(s) - blood pressure , leptin , medicine , endocrinology , waist , body mass index , obesity , blood lipids , anthropometry , diastole , cholesterol
The positive relationships between high blood pressure (BP) and obesity have been reported and leptin, adipocyte‐derived hormone, has been known to increase blood pressure. The study aimed to find out the effect of lifestyle intervention on BP in Korean men with systolic BP ≥ 130 mmHg or diastolic BP ≥ 85 mmHg. Fifty‐two men (age 42.5 ± 8.5 yrs) with normal weight (BMIs < 25 kg/m 2 ) and high BP (NH) and forty men (age 42.0 ± 8.4 yrs) with obese (BMIs ≥ 25 kg/m 2 ) and high BP (OH) underwent 5 times of 1:1 intensive counseling during 12 weeks. Anthropometric, blood pressure measurements and 24hr recall were performed, and blood levels of lipids, glucose, leptin, C‐reactive protein (CRP) were analyzed at 0 week and 12 week. In both groups, weight, body mass index, fat, waist circumference, SBP, DBP were significantly decreased after 12 weeks (p < 0.05). Similarly, TC, LDL‐C, CRP and HbA1c levels were decreased (p < 0.05). In the case of subjects with higher than 10 ng/mL of leptin level at 0 wk, percentage change of DBP were negatively associated, but only in NH (p < 0.05). Therefore, these results suggest that upon serum leptin levels at baseline, effects of lifestyle intervention would be different in Korean men.