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Acute effects of pistachio consumption on postprandial glucose and insulin levels, oxidative stress, gut satiety hormone responses and endothelial function
Author(s) -
Kendall Cyril W.C.,
Campbell Janice,
Jenkins Alexandra L.,
Jenkins David J.A.
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.971.11
Subject(s) - postprandial , meal , glycemic , medicine , insulin , food science , oxidative stress , type 2 diabetes , diabetes mellitus , endocrinology , biology
Background Nut consumption has been found to decrease risk of CHD, to improve control of type 2 diabetes and to promote healthy body weights, possibly related to their favorable fat, protein and antioxidant profiles. Previous studies have demonstrated that pistachios when included in meals decrease the postprandial glycemic response of carbohydrate foods. Methods 20 subjects, 40–65y, BMI>30kg/m 2 , with metabolic syndrome as defined by NCEP ATP III guidelines were recruited. Each subject participated in a total of 5 breakfast study meals over 5–10wks. Study meal order was randomized and were consumed after an overnight fast. Meal 1 was a control meal of white bread (50g available CHO). Meals 2 (white bread, butter and cheese) and 3 (white bread plus 3oz pistachios) had similar macronutrient profiles. Meals 4 (white bread) and 5 (3oz pistachios alone) had the same amount of available CHO (12g). Capillary finger‐prick and venous blood samples were taken and subjective satiety measures via a visual analogue scale were assessed along with endothelial function over the 3h study periods. Differences were assessed by least squares means with a Tukey adjustment for multiple comparisons.