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Effect of yhiM expression on antibiotic resistance of E. coli
Author(s) -
Evans Edward J,
Niblick Charles J,
Taylor Ann T.S.
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.966.1
Subject(s) - antibiotics , microbiology and biotechnology , antibiotic resistance , escherichia coli , mutant , bacteriophage , biology , transposable element , bacteria , gene , genetics
yhiM is an inner membrane protein from E. coli associated with reduced susceptibility to bacteriophage infection. It has also been suggested that it is involved in antibiotic resistance. This hypothesis was tested by examining the zones of clearing obtained by various antibiotics with E. coli that either contained transposon mutants of yhiM or overexpressed yhiM. No significant difference in antibiotic resistance was observed. This work was supported by the Haines Fund for the Study of Biochemistry at Wabash College.