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Effects of tomato paste on triglyceride and cholesterol level in high‐fat diet‐induced obese rats
Author(s) -
Yang jin young,
Jung JiHye,
Jin HeeMin,
Lee BoRa,
Park JungHyun,
Kim HyunSook
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.776.12
One of the leading cause of obesity in dietary high fat intake. This study was designed to investigate the effects of tomato paste on lipid metabolism in high fat diet‐induced obese rats. Rats were fed a normal diet (ND), high fat diet (HFD), HFD containing 5 or 10% tomato paste (HFD + 5% TP and HFD + 10% TP). We examined the effects of tomato paste on triglyceride (TG), total cholesterol (TC), LDL‐cholesterol (LDL‐C), HDL‐cholesterol (HDL‐C) level in plasma, liver, epididymis and feces of HFD‐induced obesity rats. White adipose tissue (WAT) and epididymal fat weight of HFD was higher than that of ND, whereas the HFD + 5% TP and HFD + 10% TP group showed significantly decreased level of those. Hematic TG, TC, LDL‐C and hepatic TC, LDL‐C, as marker of obesity, were significantly increased by high fat diet. However, hematic and hepatic TC, LDL‐C were significantly decreased in HFD + 5% TP and HFD + 10% TP. Also the level of hepatic HDL‐ C and feces TG and TC were increased in HFD + 5% TP and HFD + 10% TP groups. These results suggest that the increased plasma and hepatic levels in high fat diet induced obese rats could be down‐regulated by usage of dietary tomato paste.