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Effect of hot‐water extracts from Undaria pinnatifida sporophyll by gamma irradiation on whitening activity
Author(s) -
Yun YoungSic,
Kim DaMi,
Kim KyoungHee,
Kim JaeHun,
Sung NakYun,
Jung PilMoon,
Kim JinKyu,
Lee JuWoon,
Yook HongSun
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.771.16
This study was carried out to estimate the whitening effect of irradiated hot‐water extracts from Undaria pinnatifida sporophyll. Hot‐water extracts was sampled in Undaria pinnatifida sporophyll which is irradiated at 10, 30, 50, 70 and 100 kGy. To investigate the relationship between whitening activity of non‐irradiated and irradiated hot‐water extracts, we measured effects of tyrosinase inhibition and melanin synthesis. The contents of hot‐water extracts were increased two times by gamma irradiation compared to non‐irradiated control at 100 kGy. In tyrosinase inhibition effect, hot‐water extracts showed dose‐dependent relationship between non‐irradiated control and 10, 30, 50, 70 and 100 kGy irradiated samples and indicated that all values of irradiated samples were higher than the non‐irradiated one. Melanin synthesis using B16BL6 mouse melanoma cell stimulated with alpha MSH also showed decrease in the irradiation samples than non‐irradiated control. These results suggest that the hot‐water extracts from U. pinnatifida sporophyll appear to have more whitening activity in irradiated samples and it shows dose‐dependent relationship.