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Effect of calcium supplementation combined with fucoidan and chitooligosaccharide on cecal short‐chain fatty acid formation and calcium absorption in ovariectomized rats
Author(s) -
Kim MiHyun,
Yun Sunju,
Lee Changwon,
Surh Jeonghee
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.584.3
Pattern of short‐chain fatty acids formed in the cecum and calcium absorption of ovariectomized rats given combinations of seaweed Ca, fucoidan and chiooligosaccharide were investigated. A total 48 female wistar rats (six weeks) were used this study and 40 rats were ovariectomized, and the remaining of rats were sham‐operated. The sham and OVX‐control groups were fed standard diet (Ca 0.5%), and the left OVX groups were fed 1.0% seaweed Ca supplemented diet (SCa), 0.05% fucoidan diet (Fuco), 0.5% chitooligosaccharide diet (COS), and fucoidan + chitooligosaccharide + seaweed Ca diet (SCaFCO) for 12 weeks, respectively. Cecal acetic acid content was significantly higher in Ca group than that in OVX‐control group. Propionic acid contents were significantly higher in Fuco, COS, SCa and SCaFCO groups than that in OVX control group. There was no significant difference in apparent Ca absorption rate among the groups. In conclusion, fucoidan, chitooligosaccharide, seaweed Ca and complex of these materials may affect the intestinal fatty acid contents, it is still unclear whether Ca supplementation combined with fucoidan and chiooligosaccharide can improve the Ca absorption in intestine.