Premium
Gender and race differences in bone mineral density, fat, and lean mass among black and white prepubertal children
Author(s) -
Khan Naiman Asghar,
Richey Abby Leigh,
Drollette Eric,
Scudder Mark,
Pontifex Mathew,
Castelli Darla M,
Hillman Charles H,
Evans Ellen M
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.332.3
Although the impact of sex and ethnicity on body composition and bone status in older adults is known, in children it is incompletely characterized. This study aimed to assess the impact of sex (M and F) and race (B = Black; W = White) on fat (FAT) and lean mass (LEAN) and bone mineral density (BMD) of the whole body (WB), hip (HIP), and lumbar spine (LS) measured via DXA in 146 prepubertal children [(n) 48 W‐F, 42 W‐M, 27 B‐F, 29 B‐M]. In the absence of any interactions (p > 0.05), sex and race effects existed for FAT such that F>M (p<0.001) and B>W (p = 0.007) and for LEAN with B>W (p<0.001) however F=M (p=0.64). Similarly, with no interactions, main effects existed for BMD (all p <0.01) for WB with B>W by 7.4% and for HIP with M>F by 5.5% and B>W by 10.1%. An interaction was present for LS such that B‐F>W‐F (p<0.05); however, B‐M=W‐M (p>0.05). Sex and race effects on FAT, LEAN and BMD are apparent prior to puberty. Future work is needed to evaluate the relations among sex, race, body composition and bone status in children. Grant Funding Source: NIH HD055352