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Effects of whey protein supplements and exercise training on indices of metabolic syndrome in middle‐aged overweight/obese adults
Author(s) -
Weinheimer Eileen M,
Conley Travis B,
Kobza Vanessa M,
Sands Laura P,
Lim Eunjung,
Janle Elsa M,
Campbell Wayne W
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.223.6
Subject(s) - overweight , metabolic syndrome , medicine , waist , whey protein , endocrinology , insulin resistance , body mass index , placebo , obesity , blood pressure , area under the curve , lipid profile , cholesterol , chemistry , food science , alternative medicine , pathology
Purpose This double‐blind, randomized, placebo‐controlled, community‐based 9‐month study assessed the effects of whey protein and exercise training on indices of metabolic syndrome in middle‐aged overweight/obese adults. Methods Men (n = 88, 48 ± 8 y, 30.6 ± 2.8 kg/m 2 ) and women (n = 133, 48 ± 8 y, 29.8 ± 2.7 kg/m 2 ; mean ± SE) consumed 200 kcal supplements with 0 (n = 84), 10 (n = 82), 20 (n = 25), or 30 (n = 30) g whey protein twice daily. All subjects performed resistance (2 d/wk) and aerobic (1 d/wk) exercise. Results Among all subjects, from pre to post glucose area under the curve (AUC) was unchanged (−325 ± 227 mmol/L·3h, p=0.16), insulin AUC decreased 2.6 ± 2.3 % (−1041 ± 298 μmol/L·3h, p=0.01), and HOMA (−3.4 ± 2.6, p=0.81) and insulin sensitivity index (−0.3 ± 0.2, p=0.63) were unchanged. Furthermore, blood pressure decreased 2–3% (systolic: −3.3 ± 1.5 mmHg, p=0.01; diastolic: −1.9 ± 0.9 mmHg, p=0.03) and plasma lipid lipoprotein profile (total, LDL and HDL cholesterol and triacylglycerol), C‐reactive protein, and waist circumference were unchanged. Whey protein amount did not influence these responses. Conclusion Whey protein supplementation did not promote exercise‐induced changes in indices of metabolic syndrome in middle‐aged overweight/obese adults who maintained body weight. Grant Funding Source : US Whey Protein Research Consortium; NIH T32AG025671 and UL1 RR025761