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Ocular circulatory response to exhaustive exercise in humans
Author(s) -
IKEMURA TSUKASA,
HAYASHI NAOYUKI
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.1054.3
Subject(s) - circulatory system , medicine , cardiology
Although we have previously reported that dynamic exercise increases ocular blood flow, it is unclear whether exhaustive exercise increases ocular blood flow. To solve this question, ocular blood flow and blood pressure were measured in 12 healthy subjects. Subjects performed a leg‐cycle exercise at 75% of maximal heat rate until exhaustion. Blood flow in the superior temporal retinal arteriole (STRA) and the retinal and choroidal vessels (RCV) were measured by using laser speckle flowmetry every 3 min during exercise. The conductance in the ocular vasculatures was calculated by dividing blood flow by the mean blood pressure (MBP). MBP significantly increased throughout the exercise. Five min after exercise began, blood flow in the RCV significantly increased by 32±6% from the resting baseline. At exhaustion, blood flow in the RCV did not significantly change, whereas that in the STRA significantly decreased by 13±4%. The conductance in the STRA and RCV significantly decreased at exhaustion. These findings suggest that exhaustive exercise decreases blood flow in the STRA with a decrease in vascular conductance, and that there is a regional difference in ocular blood flow.