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The relationships between body fatness and thermoregulatory system in different seasons
Author(s) -
Kanikowska Dominika,
Sato Maki,
Iwase Satoshi,
Nishimura Naoki,
Shimizu Yuuki,
Inukai Yoko,
Sugenoya Junichi
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.1053.30
Subject(s) - ghrelin , thermoregulation , leptin , sweat , endocrinology , obesity , medicine , heat stress , heat load , core temperature , zoology , biology , hormone , physics , thermodynamics
Obesity is widely recognized as an epidemic in the world; however, the impact of biological rhythms on the metabolic syndrome has received minimal attention. Patients with obesity may be more vulnerable to injury from heat stress, and appear to be inefficient thermoregulation. The purpose of this study is to highlight the association between seasonal rhythms, obesity and thermoregulatory system. We hypothesize that there will be differences in seasonal variability of thermoregulatory response and ghrelin and leptin concentrations between control and obese subjects at winter and summer seasons. Ten volunteers were subjected for the experiment at two times of the year ‐ around the summer and winter solstices at latitude 35° N. Serum leptin and ghrelin concentrations, plasma insulin, glucose, TSH, fT3,fT4 and total cholesterol concentrations were analyzed before the water immersion. Seasonal changes in the thermoregulatory responses were assessed by measuring core and sweat rate during immersion of the leg in hot water (at 42°C) for 30 min in the room maintained at 26 °C. Tympanic temperature and sweat rate during water immersion show significant differences between seasons.