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Comparison of Pulmonary Artery Blood and Intestinal Temperatures in Humans
Author(s) -
Pearson James,
Ganio Matthew S,
Seifert Thomas,
Overgaard Morten,
Secher Niels H,
Crandall Craig G
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.25.1_supplement.1053.11
Subject(s) - thermistor , heat stress , core temperature , medicine , pulmonary artery , thermoregulation , core (optical fiber) , hyperthermia , zoology , chemistry , materials science , biology , electrical engineering , composite material , engineering
In humans, whole body heat stress is commonly used to address physiological questions where the measurement of “core temperature” is central to the investigated hypothesis. However, the temperature at different body sites often used in the measurement of core temperature likely varies. This study compared pulmonary artery blood temperature (via thermistor in a pulmonary artery catheter) with intestinal temperature (telemetry pill) during whole‐body heating, followed by rapid whole‐body cooling in 11 males (mean ± SD age 24 ± 3 yrs; height 181 ± 7 cm; mass 77.5 ± 8.1 kg). To impose heating and cooling, subjects wore a tube lined suit that was circulated with either hot (48–50°C) or cool (10–15°C) water, respectively. Prior to heat stress blood temperature (36.77 ± 0.26°C) was less than intestinal temperature (37.04 ± 0.27°C, P < 0.001). However, the increase in temperature with heat stress was similar between sites (blood Δ = 1.26 ± 0.19°C vs. intestinal Δ = 1.14 ± 0.37°C; P = 0.13). With subsequent cooling, the decrease in blood temperature (Δ = −0.74 ± 0.38°C) was greater than intestinal temperature (Δ = −0.17 ± 0.55°C, P = 0.01). These data highlight the differences in temperature between measurement sites particularly during cooling following a heat stress, thereby showing that the interpretation of “core temperature” is dependent upon the measurement site. Supported by NIH Grants HL61388 & HL84072