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Identification of keratin 10 in a novel threadlike‐structure, Bonghan ducts and corpuscles
Author(s) -
Kim Sorim,
Lee Seul Ki,
Jang Soo Hwa,
Choi Jae Hong,
Lee Byung Cheon,
Lee So Yeong,
Ryu Pan Dong
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.lb596
Subject(s) - keratin , western blot , biology , messenger rna , anatomy , pathology , gene , genetics , medicine
Keratin 10 (K10) is one of the major keratins involved in keratinoncytes differentiation and keratinization. In the present study, we examined the expression of K10 in the novel thread‐like structures (NTS) composed of Bonghan ducts and corpuscles located on the surface of the rat abdominal organs. The K10 mRNA and protein was identified by RT‐PCR and Western blot analysis. The K10 immunoreactivities were detected in a follicle‐like structure that covers several cells inside the NTS. Taken together, NTS expresses K10, in particular, in its internal structure. This is the first report demonstrating the expression of K10 in the NTS and may help to understand the structure and function of the NTS.