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Estimates of Body Composition in Drug Naïve Asymptomatic HIV‐infected Rural Kenyan Women
Author(s) -
Ernst Judith Ann,
Ettyang Grace,
Katschke Adrian,
Lewis Brian,
Neumann Charlotte
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.lb373
Subject(s) - bioelectrical impedance analysis , anthropometry , asymptomatic , fat free mass , lean body mass , medicine , human immunodeficiency virus (hiv) , fat mass , wasting , body water , zoology , kenya , demography , body mass index , body weight , biology , immunology , ecology , sociology
Objective Bioelectrical impedance analysis (BIA), as a method to estimate fat free mass (FFM) and % body fat (%BF), is compared to the anthropometric (Anthro) method using skinfold (SF) and body circumference (BC) measures in HIV‐infected women in rural Kenya. Methods In 138 women, (WHO Stage 1 or 2; CD4 > 250 cells/uL), height, weight, SF, BC and BIA were obtained with standardized procedures. Fat area of the arm (MAFA), muscle area of the arm (MAMA), thigh (MTMA), calf (MCMA) and sum of SF were calculated from standard equations using BC and SF. Estimates of FFM, %BF and total body water (TBW) from BIA measures of resistance were calculated with standard equations. Results The mean (SD) for age, BMI and CD4 was 36.4(7.5) yrs, 22.3(3.6); 11% < 18.5, and 492(191) cells/uL, respectively. Anthro compared to BIA for estimates of lean and fat massAnthro MAMA MTMA MCMA MAMA MAFA Sum SFBIA FFM FFM FFM TBW %BF %BF __ r 0.61 0.70 0.71 0.65 0.84 0.87 __All correlations p<0.001Conclusions BIA, when compared to the method using anthropometry measures, has a strong relationship to fat and lean mass, at baseline, in drug naïve asymptomatic HIV‐infected rural Kenyan women enrolled in an 18 month randomized controlled field trial that measures the impact of added protein and energy on body composition. Supported in part by USAID Grant No. PCE‐G‐00‐98‐00036‐00 and 1R01HD57646‐01A1 (CFDA #93.865)