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The effect of electroacupuncture on bladder dysfunction caused by streptozotocin‐induced diabetes
Author(s) -
Liao JiuanMiaw,
Lin TzerBin,
Liou YingMing
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.986.10
Subject(s) - zusanli , electroacupuncture , medicine , cystometry , diabetes mellitus , urology , streptozotocin , acupuncture , urinary bladder , endocrinology , pathology , alternative medicine
Diabetic bladder dysfunction (DBD) is a most common complication of diabetes mellitus (DM) with poorly effective treatment options. This study examined the effect in bladder function following 1, 3, and 5 wk electro‐acupuncture (Ea) treated at Zusanli (ST‐36) acupoints (100 Hz, 0.5mA, 1.5–2ms, under conscious condition, 30 min per day) of streptozotocin (STZ) induced‐DM rats compared with that in age‐matched non‐Ea treated diabetic group, and shamed‐treated control group. Urodynamic parameters were assessed by cystometry in addition to the measurements of urinary functional changes. Diabetes resulted in decreased body weight. Bladder weight, voiding volume, and bladder capacity increased in both the non‐Ea and Ea‐treated DM groups. Peak voiding pressure (PVP) and the intercontraction interval (ICI) increased in the non‐Ea‐ and 1wk Ea‐treated DM groups. However, in 3 and 5wk Ea‐treated DM groups, PVP was showed no significantly different compared with the sham‐treated control group. Similar changes in the compliance and emptying ability of the bladder were seen in the 3 and 5wk Ea treated groups. Long‐term Ea‐treated at Zusanli acupoints effectively ameliorated a few funtional changes in bladder function. These results suggest that such a therapeutic technique has potential in clinical practice.