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Blood Pressure is Associated with BMI and Predicts Plasma Glucose Control and Triglycerides among Obese Latinos with Type 2 Diabetes
Author(s) -
Chhabra Jyoti,
VegaLópez Sonia,
D'Agostino Darrin,
Fernandes Maria Luz,
SeguraPérez Sofia,
Damio Grace,
PérezEscamilla Rafael
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.935.3
Subject(s) - medicine , endocrinology , blood pressure , overweight , type 2 diabetes , population , hemoglobin , diabetes mellitus , metabolic syndrome , diastole , obesity , environmental health
The objective of this study was to examine the relationship of BMI, diastolic and systolic blood pressure (DBP, SBP), Triglycerides (TG), HDL‐Cholesterol (C), LDL‐C, Fasting Plasma Glucose (FPG), and Glycosylated Hemoglobin (HbA1c) in Latino patients with type 2 diabetes (T2D). Demographic information was gathered. Weight and height were measured. Blood sample was obtained from 211 patients ≥21 yrs, HbA1c ≥7, residing in Hartford county (M=26.5%; F=73.5%). Means: age=56.4±11.8 yrs, BMI=33.7±7.8 kg/m 2 , SBP=120±15.8 mm Hg, DBP=68.4±9.6 mm Hg, TG=153±95 mg/dL, HDL‐C=51±14 mg/dL, LDL‐C=98±39 mg/dL, FPG=10.4±4.5 mmol/dl (187.2±81 mg/dl), HbA1c=9.6±1.8%. 120 patients had a diagnosis of hypertension. Linear regression results revealed that BMI was related only to diastolic BP (adj. R 2 =0.02, Std. β=0.14, p≤0.04). DBP predicted FPG (adj. R 2 =0.03, Std. β=0.19, p≤0.01). On regressing both DBP and TG predicting FPG, only TG was significant (adj. R 2 =0.13, Std. β DBP =0.10 (p=0.15), Std. β TG =0.35(p≤0.00)). FPG was related with HbA1c (adj. R 2 =0.24, Std. β=0.5, p≤0.00). In an overweight/obese population, the relationship between BMI and plasma glucose among individuals with T2D may be mediated by other metabolic syndrome indicators, such as diastolic BP and TG. Funding: Connecticut NIH Export Center of Excellence for Eliminating Health Disparities among Latinos (NIH‐NCMHD grant # P20MD001765).