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Physical exercise practice influences serum concentrations of 25(OH)D and PTH in spinal cord injured men.
Author(s) -
Chain Amina,
Koury Josely C,
Figueiredo Flávia A,
d'Oliveira Giselle LC,
Bezerra Flávia F
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.917.14
Subject(s) - medicine , vitamin d and neurology , spinal cord , spinal cord injury , serum concentration , endocrinology , physical activity , physical therapy , psychiatry
The aim of the study was to evaluate the influence of physical exercise practice on serum concentrations of 25(OH)D and PTH in spinal cord injured adult men (19–56 y, n = 25). Hours of training per week were estimated by using a self‐reported questionnaire. Serum concentrations of 25(OH)D and intact PTH were assessed by a chemiluminescent enzyme‐labeled immunometric assay. Serum 25(OH)D varied in a range between 27.5–107.5 nmol/L, being 15 subjects below 75 nmol/L and 3 subjects below 50 nmol/L. Serum iPTH was on average 44.9 ± 15.0 pg/mL and correlated negatively with 25(OH)D (r= −0.45, P<0.05). Hours of physical exercise practice was on average 9 ± 11 h/week. After controlling for age and time after injury, hours of training per week was positively correlated with serum 25(OH)D (r= 0.54, P<0.05) and negatively correlated with serum iPTH (r= −0.54, P<0.05). Our results indicate that most of the spinal cord injured men studied had serum 25(OH)D concentrations below the proposed cutoff (≤ 75nmol/L) to define insufficiency. Moreover, these results suggest that physical exercise practice may contribute for improving vitamin D status in adult spinal cord injured men. Financial support: FAPERJ (Brazil).