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Effects of regular endurance exercise on brachial blood flow response to mental stress
Author(s) -
Komine Hidehiko,
Takai Yohei,
Akazawa Nobuhiko,
Maeda Seiji,
Yoshizawa Mutsuko,
Sugawara Jun,
Yokoi Takashi
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.804.5
Subject(s) - brachial artery , vasodilation , medicine , blood flow , cardiology , endothelium , nitric oxide , mental stress , blood pressure
Muscle vasodilator response to mental stress is partly mediated by nitric oxide (NO). Regular endurance exercise augments NO‐mediated endothelium‐dependent vasodilator function. We therefore tested the hypothesis that regular endurance exercise augments NO‐mediated endothelium‐dependent vasodilator function, and thereby enhances muscle blood flow response to mental stress. To examine this hypothesis, we measured brachial blood flow response to 3 min of mental arithmetic using Doppler ultrasound in sedentary and endurance trained young men. To assess NO‐mediated endothelium‐dependent vasodilator function, we measured flow‐mediated vasodilatation (FMD) of the brachial artery using ultrasound imaging. Brachial blood flow was increased during mental arithmetic both in the sedentary and the endurance trained group, but the increase in blood flow was less in the trained group. FMD of the brachial artery did not differ between the groups. These results suggest that regular endurance exercise in young men blunts brachial blood flow response to mental arithmetic, which is irrespective of endothelium‐dependent vasodilator function of the brachial artery.