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Glycine and Other Metabolic Enhancers (ME) to Fill Deficiencies
Author(s) -
Hubbard Richard,
Chambers Jeff
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.745.8
Subject(s) - omnivore , arginine , glycine , histidine , endocrinology , medicine , morning , urine , chemistry , biochemistry , amino acid , biology , paleontology , predation
This is a continuing evaluation of analysis data from our 2009 study on the safety and efficacy of our supplement mixture as metabolic enhancers (ME) (Proc Soc, 23 B98 2009). This second report on our supplement use is emphasizing the supplemented glycine and arginine along with our other ME materials. As before, the subjects are from 58 to 83 years of age, as 10 male and 11 females, who were either on a self choice vegetarian (vegan) diet or omnivore diet as verified by dietary questionnaire and diet confirmed by urinary ratio of histidine/1‐methyl histidine (Hubbard, RW, J. Nutr. 1995;125:2333). First morning urines at the start of the 3 month supplement period, were analyzed for glycine, arginine 1‐methylhistidine and histidine (Hubbard RW et al. J. Chrom 1988;431:163) with random draw at one of three start times for each of the clinical subjects. There were no significant changes in arginine levels. Glycine differences after supplementation, pre and post for vegans had a p=0.138, and for omnivores p=0.73 change. Urinary histidine levels for vegans showed no significant change before and after supplementation, but omnivore histidine levels were significantly lower (p=0.02) both pre‐and post than the vegans indicating that omnivores secrete significantly less histidine, from our data, than omnivores (p=0.01).