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Dietary supplementation with L‐glutamine and AminoGut ™ enhances protein synthesis in chicken skeletal muscle
Author(s) -
Li Peng,
Kim Sung Woo,
Nakagawa Kazuki,
Zhou Huaijun,
Wu Guoyao
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.740.21
Subject(s) - broiler , glutamine , medicine , endocrinology , phenylalanine , skeletal muscle , jejunum , starter , feed conversion ratio , chemistry , biology , zoology , amino acid , biochemistry , food science , body weight
This study determined if dietary supplementation with 0% (Control), 1% L‐glutamine (Gln), 1% L‐glutamate (Glu), or 1% AminoGut ™ (a mixture of Gln and Glu) on protein synthesis in chicken muscle. Within 8 h after hatching, 40 broiler chickens were assigned randomly to 4 dietary treatments (10 chicks per group): 0%, 1% Gln, 1% Glu, or 1% AminoGut ™ . All diets were made isonitrogenous by addition of L‐alanine. Chicks had free access to starter and grower diets between d 1–14 and d 15–35, respectively. On d 35, fractional rates of protein synthesis (FRPS) in tissues were measured using the 3 H‐phenylalanine flooding dose technique. Compared with the control group, dietary supplementation with Gln or AminoGut ™ did not affect (P>0.05) feed intake, but increased (P<0.05) Gln concentrations in plasma (26–28%). Gln and AminoGut ™ supplementation enhanced (P<0.05) FRPS in breast muscle (33–37%) and leg muscle (28–32%), but did not affect (P>0.05) protein synthesis in liver or jejunum. Glu supplementation had no effect (P>0.05) on any of the measured parameters. These results indicate that dietary supplementation with Gln or AminoGut ™ promotes chicken growth through stimulating muscle protein synthesis.