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Validation of Finger‐Prick Testing of FBG, TC, and HbA 1c in Adolescents
Author(s) -
Barret Sheila C.,
Huffman Fatma G.,
Johnson Paulette
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.739.6
Subject(s) - medicine , venous blood , limits of agreement , mean difference , significant difference , population , nuclear medicine , confidence interval , environmental health
The study compared finger‐prick testing of FBG, TC and HbA 1c with venous blood method in Jamaican adolescents in a school setting. Adolescents ages 14–18 years were studied. Subjects were randomly selected from grades 9–12, in ten high schools on the island. Capillary whole blood was tested for fasting blood glucose, total cholesterol, and HbA 1c . Finger‐prick testing was compared tovenous blood using standard laboratory procedures for all three tests. A total of 59 adolescents participated, mean age was 15.6±1.2 years. Mean FBG values were 92.97±11.98 for finger‐prick and 95.24±10.27 for venous sample. No significant difference was found for methods of testing for FBG (p >.05). Mean venous value of TC(157.9±30.0) was significantly higher (p <.01) than finger‐prick (145.8±21.6). Mean venous HbA 1c (5.40±0.81) was significantly lower (p<.01) than finger‐prick (6.08±1.5). Percentage bias between the two methods met the reference standards for FBG, and TC but not for HbA 1c . Bland Altman tests of agreement between the two methods indicated good agreement for all three tests. Finger‐prick testing of FBG compared favorably with venous testing and may be used for screening this population. The Bland Altman tests for agreement indicated that finger‐prick testing of FBG, TC, and HbA 1c may be used for the screening of adolescents. Supported by a grant from FIU Foundation.