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Effect of Dietary Sodium and Potassium Intervention on Blood Glucose
Author(s) -
Bazzano Lydia Angela Louise,
Gu Dongfeng,
Chen ChungShiuan,
Huang Jianfeng,
Chen Jing,
Rao Dabeeru,
Jaquish Cashell,
James Hixson,
Duan Xiufang,
Chen Jichun,
Kelly Tanika,
Rice Treva,
Hamm L. Lee,
Whelton Paul,
He Jiang
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.739.2
Subject(s) - potassium , medicine , sodium , salt (chemistry) , zoology , dietary salt , endocrinology , chemistry , blood pressure , biology , organic chemistry
Studies have suggested that a low salt intake may increase blood glucose. We examined blood glucose responses to dietary sodium and potassium interventions among 1,906 GenSalt study participants in rural China. Dietary intervention included a 7‐day low‐salt feeding (51.3 mmol/day), a 7‐day high‐salt feeding (307.8 mmol/day), and a 7‐day high‐salt feeding (307.8 mmol/day) plus potassium supplementation (60 mmol/day). Overnight fasting blood samples were drawn at baseline and at the end of each of the intervention periods. Mean (SE) change from baseline to low salt diet was 3.14 (0.27) mg/dL from the low salt to high salt diet, −4.70 (0.22) mg/dL, and from high salt to high salt plus potassium supplementation, −0.69 (0.22) mg/dL. These results suggest that statistically significant changes in blood glucose may occur during the initiation of a low salt diet. However these changes are small and their clinical significance is unclear. In our study, diets were only implemented for 7 days, thus further studies should be conducted which examine the duration of these changes after a low salt diet is initiated.