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Nutritional and inflammatory markers in gastroenterological surgical patients. Influence on postoperative complications
Author(s) -
Zago Liliana,
Danguise Eduardo,
Infantino Carlos González,
Río María Esther,
Callegari Mariana
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.724.7
Subject(s) - gastroenterology , medicine , albumin , transthyretin , vitamin
The relevant importance of nutrition and inflammation on the outcome of the surgical patient is well recognized. In order to evaluate their influence on appearance of complications, 50 patients from programmed gastroenterological surgeries were studied. BMI, vitamin A and C, Zn, albumin (Alb), transtiretin (TTR), RBP, α1‐acid glycoprotein (AGP) and PCR were determine in fasting samples taken before surgical procedure. After follow up, 43 patients with complete information were analyzed. Complications appeared in 17 patients (39.5%). Patients with complications (C) presented lower values of vitamin A (36.9±14.5 vs 49.7±20.6 μg/dl; 18% vs 4% <25 μg/dl), vitamin C (0.60±0.39 vs 0.70±0.44; 41% vs 24% < 0.4 mg/dl) and Zn (78.4±25.8 vs 87.8±25.7; 35% vs 11% < 70 μg/dl), and higher values of AGP (100.1±50.9 vs 79.1±36.7 mg/dl) and PCR (1.67±1.99 vs 1.15±1.78 mg/dl); only significant mean difference of vitamin A was founded (P=0.0318), because of high dispersion of data. No difference was observed in Alb (4.1±0.7 vs 4.2±0.5g/dl), TTR (22.5±10.1 vs 24.7±7.5 mg/dl) and RBP (3.6±1.3 vs 4.2±1.9 mg/dl), but a higher % of patients with low values was observed in C patients (29% vs 12% for Alb, 47% vs 27% for TTR and 47% vs 29% for RBP). We conclude that combination of higher nutritional impairment and inflammation may influence appearance of complications. Plasma vitamin A, C and Zn are the most promissory risk markers. Supported by UBACyT B090.