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Effect of almond consumption on the serum fatty acid profile: a dose response study
Author(s) -
Kendall Cyril WC,
Nishi Stephanie,
Yoon AnaMaria,
Esfahani Amin,
Bazinet Richard P,
Lapsey Karen G,
Jenkins David JA
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.564.16
Subject(s) - oleic acid , blood lipids , fatty acid , crossover study , food science , lipid profile , cholesterol , medicine , chemistry , zoology , biochemistry , biology , alternative medicine , pathology , placebo
Background Studies indicate that diets high in monounsaturated fatty acids (MUFA) can improve the blood fatty acid profile, by elevating oleic acid concentrations, and as such, relate to a decreased risk of coronary heart disease (CHD). Almonds are a good source of MUFA. Objective To assess the dose‐response effect of almonds compared to low‐fat muffins on the blood fatty acid profile and blood lipid risk factors of CHD in hyperlipidemic subjects. Design In a randomized controlled crossover study, 27 hyperlipidemic men and women consumed three iso‐energetic (mean 423 kcal/d) supplements in one‐month phases. The supplements consisted of full‐dose almonds (50–100g/d), half‐dose almonds with half‐dose muffins, and full‐dose muffins. Fasting blood was obtained at weeks 0 and 4 of each treatment. Results On both the half‐ and full‐dose almond supplements, there were significant increases in the oleic acid fraction of the blood lipid fractions. In addition, significant reductions were seen, respectively, for Total‐C (P=0.035; P=0.002), LDL‐C (P=0.021; P<0.001), Total:HDL‐C (P=0.003; P<0.001) and LDL:HDL‐C (P=0.002; P<0.001) with increases in HDL‐C (P=0.021; P=0.014). Conclusion Almond consumption significantly increased the oleic acid content of the blood lipid fractions and significantly improved blood lipid risk factors for CHD. (Funded by the Almond Board of California)