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Effect of strawberry powder on blood pressure and flow mediated vasodilation in individuals with pre‐hypertension
Author(s) -
VauxBjerke Alison,
Kan Flora,
Barrette Taryn,
Edirisinghe Indika,
BurtonFreeman Britt,
Kappagoda Tissa
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.564.13
Subject(s) - blood pressure , medicine , vasodilation , ambulatory blood pressure , placebo , diastole , ex vivo , blood flow , ambulatory , in vivo , cardiology , endocrinology , biology , pathology , alternative medicine , microbiology and biotechnology
We previously reported that strawberry (Str) extract induced endothelium dependent relaxation in an ex vivo rabbit aorta model, suggesting a role for Str in blood pressure regulation. Based on this data, we hypothesized that daily consumption of strawberry powder at a dose corresponding to ex vivo results for 8 wks will reduce blood pressure (BP) and increase vessel relaxation (as measured by flow mediated vasodilation, FMD) in pre‐hypertensive [systolic pressure (sys) 120–139 mmHg and diastolic (dia) 80–89 mmHg] men and women. In a randomized, parallel, double‐blind, placebo‐controlled trial, men and women (n=32, 43 ± 12 y) consumed either a placebo (Pbo) or Str (12 g Str powder, ~136 mg flavonoids) beverage matched in energy and macronutrient composition. BP data was collected via 24h ambulatory BP monitors at screening, wks 1, 4, 8, and 4 wks post‐study. FMD was measured at wks −2 and 8. After 8 wks of intervention, the Str group had a 2.1% ± 1.7% mmHg decrease in sys BP and 1.7% mmHg decrease in dia BP corresponding to decreases of 3.2% and 2.1% mmHg when compared to sys and dia BP in subjects consuming Pbo, respectively. FMD increased 3.5% ± 2.1% in women consuming Str and decreased 2.5% ± 1.8% in men; suggesting a diet by sex interaction. More research is needed to strengthen this association; however it appears strawberry consumption may benefit individuals with pre‐hypertension.