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Compliance of energy and protein intake correlates with changes in renal functions of patients with chronic kidney disease
Author(s) -
Chen MeiEn,
Hwang ShangJyh,
Chen HungChun,
Huang MengChuan
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.557.1
Subject(s) - renal function , medicine , kidney disease , creatinine , confounding , endocrinology , gastroenterology
Dietary energy and protein play important roles in progression of chronic kidney disease (CKD) This study investigated association between compliance of energy and protein intake and changes of renal functions in CKD. Adult patients (n=377) diagnosed with CKD 3–5 stages were recruited and continuously received nutrition education by registered dietitians during a mean of 1.5 years. Dietary energy and protein intake were characterized based on a ratio (IR) of actual vs.recommended intake by registered dietitians X100%. Fair dietary compliance was defined as energy IR% ≥90% and protein IR < 110% and poor compliance as energy IR% < 90% and protein IR ≥110%. Distribution of patients with fair dietary compliance increased from 41.7% at baseline to 58.3% after a mean of 1.5 year follow‐up (p<0.001). After adjusting for confounders, increases in every 100 kcal energy intake per day was positively correlated with glomerular filtration rate (GFR) (beta=0.465, SE=0.161, p=0.004) and negatively associated with creatinine (beta=−0.083, SE=0.032, p=0.011) after 1.5 year follow‐up. In contrast, increases in every 7 grams of dietary protein marginally correlated with decreases in GFR at increment of 0.431 ml/min/1.73m 2 (SE=0.24, p=0.073) and increases in creatinine at 0.088 mg/dl (SE=0.048, p=0.069). Nutrition counseling and compliance of energy and protein intake appear to be beneficial in CKD progression.