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Influence of honey versus sucrose on glucose, insulin and lipid responses in mice
Author(s) -
Nemoseck Tricia,
Cole Sarah,
Petrisko Yumi,
Hong Mee Young,
Kern Mark
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.553.6
Subject(s) - weanling , sucrose , triglyceride , insulin , cholesterol , carbohydrate , dietary sucrose , endocrinology , chemistry , medicine , biology , food science
We previously reported that honey may reduce weight gain and adiposity compared to sucrose in adult rats. Our goal was to determine the influence of honey versus sucrose on adiposity and plasma concentrations of glucose, insulin and lipids in weanling mice. Thirty male ICR mice (34.0 ± 2.4g) were equally divided into two groups and fed ad libitum one of two isoenergetic diets differing only in a portion of the carbohydrate provided. Diets contained 20% carbohydrate (by weight of total diet) from either clover honey or sucrose. After 34 days, fat pads were excised and blood was collected. Weight gain and fat pad weights were similar (p>.05) between mice fed honey and sucrose. Non‐fasting plasma glucose and fasting glucose and insulin levels were lower (p≤.05) by 11%, 21% and 33%, respectively, for honey‐fed mice compared to sucrose‐fed mice. Total cholesterol was 18% higher (p≤.05) for mice fed honey versus sucrose: however, no differences (p>.05) in triglyceride or HDL‐cholesterol levels were detected. These results suggest that in comparison to sucrose, consuming a diet containing honey may promote better glucose control but worse cholesterol concentrations while not altering adiposity in young, growing mice. More research is necessary to better understand the possible health influences of honey versus refined sugars following acute and long‐term exposures. Sponsored by American Heart Association