Microbiological evaluation of 3‐((E)‐(4‐chloro‐6‐hydroxypyrimidin‐2‐ylimino)methyl)‐4‐chloro‐2H‐chromen‐2‐one

3‐((E)‐(4‐chloro‐6‐hydroxypyrimidin‐2‐ylimino)methyl)‐4‐chloro‐2H‐chromen‐2‐one 3 is synthesized in very good yields by reaction of corresponding 4‐chloro‐2‐oxo‐2H‐chromene‐3‐carbaldehyde 1 and 2‐amino‐6‐chloropyrimidin‐4‐ol 2 . Antibacterial activity of products 3 is investigated and results are submitted for their activities against Escherichia coli and Enterochoaco . Applying the disc method we mesasured diameters of the inhibition zone around disc which are previously wetted with N,N‐DMF solution of compounds 3 in concentration 1 mg/l, 0.5 mg/l and 0.1 mg/l. The compounds 3 showed strong activity in reducing the microbial growth. The synthesized compound 3 showed most effective antibacterial activity against Escherichia coli.