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Development and use of a computer model to predict and compare how changing macronutrient composition influences changes in weight and body composition
Author(s) -
Sakita Saori,
Davidson Robert T
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.343.1
Subject(s) - composition (language) , energy balance , calorie , body weight , food composition data , chemistry , food science , zoology , biology , ecology , endocrinology , philosophy , linguistics , orange (colour)
There are many different approaches to weight loss diets. The macronutrient composition of these can vary tremendously for any given energy level. How the body processes and utilizes the varying amounts of macronutrients can have a significant effect with energy balance on the composition of the resultant weight change. We hypothesized that a physiologically‐based mathematical model could be constructed which would accurately describe the changes in body composition seen with a change in energy level or dietary macronutrient composition. With the STELLA modeling software and using dose‐response relationships between macronutrient intake and energy oxidation as identified in the published scientific literature, we developed a multi‐compartment model which was then validated using separately available data. Using this model, weight changes and body composition changes were typically within 10% of reported values when subjects were either at energy balance or underfed (i.e. low calorie diet). This model may be used to identify or compare expected changes in body composition due to macronutrient composition or changes in macronutrient composition.