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Longitudinal Association between Weight Gain and Hypertension: China Health and Nutrition Survey, 1991—2006
Author(s) -
Du Shufa,
Wang Huijun,
Wang Xiaoshan,
Popkin Barry M
Publication year - 2010
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.24.1_supplement.105.2
Subject(s) - overweight , medicine , weight gain , blood pressure , odds ratio , population , demography , obesity , body weight , environmental health , sociology
While studies showed that weight gain may increase the risk of hypertension, there are ethnic differences in associations and few studies among the Chinese population. Using longitudinal data on 46,601 subjects aged 18—69 y followed over six waves of the China Health and Nutrition Survey, we studied the effect of weight gain on blood pressure and hypertension. Trained nutritionists obtained weighed dietary data over 3 days combined with individual 24‐h records. Trained physicians collected 3 measures of blood pressure with a 30‐secondinterval between cuff inflations, weight and height data with standardized methods. Pattern mixture generalized linear mixed model was used to estimate the association. The average follow‐up was 7.5 years (2–15). Prevalence of hypertension increased rapidly from 15% in 1991 to 27.8% in 2006. The cumulative incident hypertension was 23.9%. The odds ratio (OR) of weight gain (1 kg/year) was 1.14 (95%CI: 1.10—1.20, p<0.01), controlled for age and weight at baseline, gender, education, overweight status and interaction between weight gain and overweight and other dummies. Sodium intake did not modify this relationship. Weight gain significantly increased the risk of hypertension in Chinese, particularly in the overweight and obese population. This research was supported by NIH R01‐HD30880.