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Bone mineral density is affected by calcium nutritional status when assessed by ultrasound in school girls
Author(s) -
Rio Maria E,
Dupraz Hernán,
Felipoff Ana Lia,
Zago Liliana,
Linari María,
Piazza Norma
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.913.2
Subject(s) - densitometry , bone mineral , calcium , creatinine , bone mass , bone remodeling , osteoporosis , ultrasound , urine , chemistry , medicine , endocrinology , radiology
Grow process is a state of high bone turnover and an inadequate calcium nutritional status can lead to suboptimal peak bone mass and predispose to osteoporosis in adulthood. Previously, we have found that the a‐CTX marker of bone growth was highly affected by body Ca status. A similar study was carried out in relation to bone densitometry. For that, urine basal samples were obtained from 120 healthy girls, aged 5.8 to 9.2 years, attending public schools of Vicente Lopez (Bs. As) and over them Ca (AAS) and creatinine (Cr) (Wiener Lab® . Argentina) were determined to calculate Ca/ Cr ratio as marker of Ca status. Bone densitometry was assessed by ultrasound (Sahara Olohi. USA) and expressed as Quantitative Ultrasonic Index (QUI). The relation: QUI vs Ca/Cr divided in five ranges between < 0,10 and >0,15, fits a quadratic function so that QUI=92,828e 0,3426x ; R2=0,78; p<0,01. Results show a quite good no linear correlation presenting a flat area between Ca/Cr <0,07‐0.01 and then ahead a significant positive slope. As in the case of the evolution of the CTX bone marker previously studied, a Ca/Cc >0,01 was mandatory during bone growth to allow the age dependent increase in bone mineralization. Supported by UBCyT US.B/735. HD PhD Thesis. Fellow from UBA