Premium
Anti‐inflammatory effects of camelina sativa oil in postmenopausal women
Author(s) -
Campbell Christina Gayer,
Picotte Mindi S.,
Syndergaard Sarah,
Filipowicz Rebecca,
Thorland William G.
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.910.14
Subject(s) - camelina , camelina sativa , sunflower oil , zoology , food science , weight gain , meal , overweight , obesity , avena , chemistry , medicine , biology , body weight , botany , agronomy , crop
Camelina sativa is a novel plant source of alpha‐linolenic acid (ALA) with a similar fatty acid profile to flaxseed. A double‐blind parallel‐arm pilot study investigated the anti‐inflammatory effects of daily consumption of camelina sativa oil for 6 weeks. Twenty overweight women (mean ± SD; 28.0 ± 2.6 kg/m 2 ) were randomized to one of two groups: 2T/d camelina oil (CO)(8g ALA/d) (n=10) or 2T/d sunflower oil (SO)(0g ALA/d)(n=10). Subjects consumed an ad libitum diet; test foods provided as baked goods. Weight significantly increased over time for both groups (CO: 70.8 ± 4.9 kg vs. 75.3 ± 7.8 kg; SO: 77.2 ± 10.2 kg vs. 79.4 ± 10.7 kg)(P<0.05). C‐reactive protein decreased 19.4% and increased 57% for the CO and SO groups, respectively (P>0.05). Plasma interleukin‐6 concentrations increased 2.8% for the CO group and 17.5% for the SO group (P>0.05). Results from this pilot study suggest that CO, an omega‐3 rich oil may provide anti‐inflammatory responses as compared to SO despite weight gain. Future research is warranted with more controlled feeding interventions that minimize weight gain. Funding was provided by Biobased Institute of Montana (USDA‐CREES 2005‐34510‐15726).