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Medicinal use of vinegar should be accompanied by a diet rich in potassium alkali salts to avoid possibility of low grade metabolic acidosis
Author(s) -
Appel Christy L,
Johnston Carol S
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.902.12
Subject(s) - urine , crossover study , potassium , ingestion , chemistry , acidosis , metabolic acidosis , food science , alkali metal , zoology , medicine , placebo , biochemistry , biology , alternative medicine , organic chemistry , pathology
Although daily ingestion of vinegar may help manage blood glucose, vinegar can decrease urine pH and possibly exacerbate low grade metabolic acidosis (LGMA). We examined if daily ingestion of vinegar or control would decrease urine pH in a randomized, crossover trial. Because change in urine pH may be buffered by dietary intake of potassium (K) alkali salts, we also determined the impact of K status on urine pH during the trial. Healthy subjects (3 M, 7 F, age 27.7±3.1 y [mean±SEM], BMI 24.9±2.0 kg/m 2 ) ingested 2 tablespoons of vinegar (VIN) or cranberry juice (CON) twice daily for 3 d with a 2 wk washout period. While no pH change was noted with the CON treatment, mean 24 h urine pH after 3 d with the VIN treatment was significantly more acidic if K status was low versus adequate (pH 5.62±0.10 versus 6.24±0.11, P =0.015). Low K status was defined as baseline 24 h urine K <50 mmol/L (n=3). Thus, it appears that high intake of K‐alkali salts enhances base‐forming capacity to buffer the acid load associated with vinegar. Persons using vinegar medicinally may benefit from consuming vinegar with K‐alkali rich plant foods to avoid LGMA. This research was supported by the ASU Nutrition Research Fund. Grant Funding Source ASU Nutrition Research Fund