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Accumulation of chromium and histological findings on Hybro chickens kidneys treated with Cr(VI) and vitamin C
Author(s) -
Bajraktari Ismet Dervish,
Gashi Agim Maliq,
Halili Fetah Murtez,
Sopa Ramadan,
Bislimi Kemajl,
Fetahu Shukri
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.739.11
Subject(s) - vitamin c , h&e stain , chemistry , staining , chromium , pathology , medicine , biochemistry , organic chemistry
It was investigated the effect of both the C vitamin and Cr (VI) on bioaccumulation of Cr in the hystological findings on Hybro chickens kidneys. The chickens were divided into 5 groups (I‐V), each with 10 individulas. The first, was controll group, whereas other groups were treated for 180 days orally with different concentration levels of Cr (VI) and C vitamin (10 mg dose/kg b.w). Preparation of tissues for pathology microscopy was carried out according to standard procedures, whereas staining was done with hematoxylin‐eosin. The concentration of Cr in kidneys was measured with atomic absorbtion spectroscopy (AAS) and UNICAM 929‐AA. spectrometer The results of our investigation have shown the occurence of little hystopathological changes on glomerule, intersticiel section and on blood vessels: Hydropic expansion and epithels desquamination of proximal tubules, vacoulization of cytoplasm, dylatation of distal tubules, expansion of subcapsular area of some glomerules, and a source of extravasate erythrocites in subcapsular area. Our findigs show that there were not any protective function of C vitamin with the dosage we have applied. C vitamin combined with Cr (VI) has significantly increased the bio‐accumulation of Cr in noted kidneys (ppm., FW) compared with control group chickens and those treated with only Cr (VI).