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Glycemic index (GI) and glycemic load (GL) on plasma high‐density‐lipoprotein cholesterol (HDL‐C) in Cuban Americans with and without type 2 diabetes (T2D).
Author(s) -
Huffman Fatma G,
Cooper Vanessa Y,
Zarini Gustavo G.
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.722.4
Subject(s) - medicine , type 2 diabetes , waist , glycemic , endocrinology , body mass index , high density lipoprotein , linear regression , diabetes mellitus , triglyceride , glycemic load , cholesterol , glycemic index , mathematics , statistics
The relationship between GL and GI and plasma HDL‐C levels in 324 Cuban‐Americans with and without T2D were studied. Subjects were randomly recruited in Miami‐Dade and Broward Counties, FL. GL and GI values were calculated using a FFQ, physical activity was assessed using MAQ and HDL‐C levels were analyzed in fasting plasma. Analysis included descriptive statistics, Pearson's correlations and linear regressions, controlling for age, gender, T2D status, BMI, waist circumference (WC), physical activity, smoking, cholesterol medication(s), protein (g) and total fat (g). There was a significant inverse correlation between both GL and GI with HDL‐C levels among subjects with T2D (r=‐.251, r= ‐.253, p<.001, respectively). After adjusting for all control variables, GL was a significant predictor of HDL‐C among Cuban Americans (B=‐.045, p=.003). There was a significant interaction between diabetes status and GI with HDL‐C (B=‐.998, p=.004). The linear regression showed that GI was a significant predictor of HDL‐C only among subjects with T2D (B= ‐.649, p=.004). Dietary GL is inversely correlated with HDL‐C independently of T2D status. GI is inversely correlated with HDL‐C levels only among T2D subjects which may explain their increased risk for CVD.