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ANTIDIABETIC AND ANTIDYSLIPIDEMIA EFFECTS OF CHUNGKUKJANG AND RED GINSENG‐CHUNGKUKJANG IN MILD HYPERGLYCEMIC SUBJECTS
Author(s) -
Shin SuKyoung,
Kwon JoongHo,
Jeong YongJin,
Jeon SunMin,
Kim HyeJin,
Choi JiYoung,
Do GyeongMin,
Choi MyungSook
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.719.1
Subject(s) - ginseng , chemistry , tbars , blood lipids , cholesterol , food science , enzyme , biochemistry , medicine , lipid peroxidation , alternative medicine , pathology
Red ginseng and Chungkukjang are well known as typical Korean functional foods that exhibit various bioactivities. This study was conducted to investigate blood glucose‐lowering activity of chungkukjang and red‐ginseng chungkukjang in hyperglycemic subjects. They were randomly divided into the control (starch, 2g/day), chungkukjang (CH, 20g/day) and red‐ginseng chungkukjang (RGCH, 20g/day) groups. Fasting blood glucose concentration was significantly lowered by 26% in CH group and 18% in RGCH group after 8 weeks compared to the initial value (p<0.001). The levels of blood HbA1c was significantly lowered in the CH group compared to the before supplementation (p<0.05). Total cholesterol and LDL‐cholesterol level were significantly lowered in both the CH (p<0.05) and RGCH (p<0.01) groups than in the control group. FFA level was significantly lowered in experimental groups (p<0.001). Erythrocyte TBARS level was significantly lowered in the CH and RGCH groups compared to respective initial values (p<0.01). It is considered that CH and RGCH are beneficial for regulating fasting blood glucose level and blood lipids level in the mild hyperglycemic subjects. Grant Funding Source The second stage of Brain Korea 21