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Hypoxic Exercise Training Enhances Vascular Hemodynamics and Oxygen Utilization in Skeletal Muscles
Author(s) -
Wu MinHuan,
Wang JongShyan
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.616.8
Subject(s) - hemodynamics , medicine , oxygenation , hypoxia (environmental) , cardiology , skeletal muscle , oxygen transport , gastrocnemius muscle , heart rate , ventilation (architecture) , aerobic exercise , physical therapy , anesthesia , oxygen , chemistry , blood pressure , mechanical engineering , organic chemistry , engineering
This study investigates how hypoxic exercise training impacts on vascular hemodynamic and O 2 utilization in exercising skeletal muscles. Twelve sedentary males were trained on a bicycle ergometer at about 60%VO 2max under 15% O 2 air condition for 20 minutes per day, 5 days per week for 4 weeks. Vascular hemodynamics and O 2 consumption and re‐oxygenation rate in gastrocnemius were determined by near infrared spectroscopy. Our results showed that 4 weeks of hypoxic exercise training improved subjects' aerobic fitness at ventilation threshold and maximal performance. Acute exposure to 12%O 2 decreased arterial hyperemia and venous compliance, as well as, oxygen consumption and re‐oxygenation rate in gastrocnemius at pre‐training state. However, the suppressive effects in vascular hemodynamics and tissue O 2 utilization in gastrocnemius by acute hypoxic exposure were ameliorated following the hypoxic exercise training. Therefore, we conclude that long‐term hypoxic exercise training can improve cardiopulmonary fitness and increase the tolerance to hypoxia‐limited O 2 transport and utilization in skeletal muscles.