Premium
FOUR DIFFERENT FIBERS FROM MAIZE AND TAPIOCA ARE WELL TOLERATED IN A PLACEBO‐CONTROLLED STUDY IN HUMANS
Author(s) -
Stewart Maria L,
Nikhanj Soma D,
Timm Derek A,
Thomas William,
Slavin Joanne L
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.560.1
Subject(s) - flatulence , bloating , crossover study , medicine , placebo , fiber , dietary fiber , maltodextrin , zoology , food science , dextrin , glycemic , gum arabic , starch , chemistry , insulin , biology , diarrhea , alternative medicine , organic chemistry , pathology , spray drying
Average dietary fiber intake in the United States is roughly half of the recommended amount. As new dietary fiber products are introduced to increase fiber intake, it is critical to evaluate the physiological effects of such fibers. Twenty healthy subjects completed the single blind crossover study in which 12 g/day test fiber (Pullulan, PROMITOR(tm) Resistant Starch, Soluble Fiber Dextrin, PROMITOR(tm) Soluble Corn Fiber) or placebo (maltodextrin) were consumed for 14‐day treatment periods. GI symptom surveys were completed on days 3 and 14. Subjects collected stools on days 11‐14, and diet was recorded on days 12‐14. Fasting blood samples were obtained from subjects on day 15. Each treatment period was followed by a 21 day washout. Total fiber intake increased 70% during the treatments. The four test fibers did not alter stool output or consistency. All fibers increased one or more GI symptoms (bloating, cramping, flatulence, stomach noises and GI score), but the scores were low (2.8‐5.1 out of 10). Stool pH was slightly lower for Soluble Fiber Dextrin. Fasting lipids, glucose, insulin, c‐reactive protein, or ghrelin did not change with treatment. Hunger before meals did not differ with treatment. A practical dose of these dietary fibers did not change stool weight, but different fibers had different effects on stool pH and SCFAs. All fibers were well tolerated in humans. Funded by Tate & Lyle Health and Nutrition Sciences.