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Testing A Dietary Supplement Mix For Safety and Efficacy
Author(s) -
Hubbard Richard,
Rea Brenda,
Fukuda David
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.549.1
Subject(s) - multivitamin , medicine , urine , morning , malondialdehyde , physiology , vitamin , oxidative stress
Nutritional supplements use in acutely ill patients, has been associated with statistically significant reduction in the number of non elective hospital readmissions (Gariballa et. al, AJM 2006:119:693). Also, nutritional importance of oral supplement use in lower‐limb ulcers was shown to be highly significant (Raffoul et al Nutr 2006;22:82) and multivitamin supplementation improved hematologic status in HIV‐infected women and children in Tanzania (Fawzi, et. al, Am J Clin Nutr 2007;85:1335). Twenty‐five healthy subjects were selected for this study. The 20 subjects who completing the study were 11 females and 9 males (ages 48‐ 84, mean of 67). Subjects were selected by random draw as Group A, and Group B, alternately by groups on and off supplements for 3 months. Supplements were taken with breakfast and supper with good tolerance. Supplements included: vitamins, minerals, and metabolic growth factors. C‐reactive blood levels were not significant (NS), early morning urine analysis for malondialdehyde (MDA) (NS), N‐terminal teleopeptides (NS), and the SF‐36 questionnaire for mental analysis (p<0.03) was significant for vegan females, and subjects stated they had more energy. Dietary questionnaires separated subjects as vegans or omnivores. Health questionnaires classified subjects for study participation.