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Cardiometabolic risk factors in Puerto Rican adults
Author(s) -
VanRompay Maria I.,
CastanedaSceppa Carmen,
McKeown Nicola M,
Ordovas Jose M,
Tucker Katherine L
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.547.13
Subject(s) - medicine , hypertriglyceridemia , impaired fasting glucose , type 2 diabetes , obesity , waist , insulin resistance , diabetes mellitus , population , metabolic syndrome , endocrinology , impaired glucose tolerance , cholesterol , triglyceride , environmental health
Puerto Ricans have prevalent type 2 diabetes (T2D), but few studies have examined this population. We classified 1289 Puerto Rican adults in the Boston area, aged 45 to 75 years, by T2D, impaired fasting glucose (IFG), and normal fasting glucose (NFG). We found high prevalence of T2D (39%) and IFG (24%), which were associated with lower education and physical activity, and greater lipid‐lowering and antihypertensive medication use, relative to NFG. Overall obesity (BMI = 30) and central obesity (waist circumference (WC) > 102 cm, men; > 88 cm, women) were prevalent, and higher with T2D (67.2% and 79.3%, respectively) and IFG (57.3% and 70.4%) than NFG (43.9% and 61.2%, each P < 0.0001). Of the total sample, 59‐73% had low HDL cholesterol (= 40 mg/dl men; = 50 women), 33‐70% hypertriglyceridemia (= 200 mg/dl), and 12‐32% both low HDL and hypertriglyceridemia. Of those with T2D, 73.6% had HbA1c = 7%, and 66.3% systolic blood pressure = 130 mmHg, despite frequent use of oral hypoglycemic (55.5%), insulin (25.9%) and antihypertensive medications (76.3%). Homeostasis model assessment for insulin resistance (HOMA‐IR) was significantly associated with BMI and WC and, inversely, with HDL in those with IFG and NFG. Interventions to improve the risk profile in this group are needed. This study was supported by NIH PO 5P01‐AG023394 and by the USDA, Agriculture Research Institute agreement number 58‐1950‐7‐707.