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Menopausal status modified the association between body mass index and hypertension among Filipino women
Author(s) -
Agustin Sonny Sombra,
Adair Linda,
Gultiano Socorro,
Bas Abet,
Lee Nanette
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.547.12
Subject(s) - medicine , body mass index , odds ratio , confidence interval , blood pressure , menopause , logistic regression , risk factor , obesity , gynecology , obstetrics
The study aimed to determine whether the association between body mass index (BMI) and hypertension is modified by menopausal status among Filipino women. Participants included 1,804 women (aged 38 to 71 yr) from the Cebu Longitudinal Health and Nutrition Survey. Hypertension was defined as systolic blood pressure >= 140 mmHg or diastolic blood pressure >=90 mmHg, BMI was calculated using measured weight and height, and menopausal status was based on self reports over multiple survey years. Controlling for age, smoking and fasting blood glucose levels, logistic regression analysis showed that BMI increased hypertension odds in all women. Using likelihood ratio test, we found significant interaction between BMI and menopausal status (p<0.05). Compared to premenopausal women, the effect of BMI on hypertension odds was lower among post‐menopausal women (odds ratio (95% confidence interval): 1.14, (1.10, 1.18) versus 1.09 (1.05, 1.12), respectively). Results suggest that BMI may be more of a risk factor before menopause possibly due to different competing risks associated with menopausal status. NIH 1 R03TW008133‐01, 1 R01 HL085144