Premium
Influence of honey versus sucrose on satiety and postprandial metabolism in healthy subjects
Author(s) -
Cholish Dana,
Nemoseck Tricia,
Petrisko Yumi,
Kern Mark
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.544.6
Subject(s) - postprandial , ghrelin , sucrose , crossover study , ingestion , insulin , area under the curve , food science , carbohydrate metabolism , medicine , endocrinology , chemistry , hormone , placebo , alternative medicine , pathology
We recently demonstrated that rats consuming a honey‐based diet gained less body weight and fat and ate less food versus rats consuming a sucrose‐based diet. The objectives of this study were to assess the effects of honey compared to sucrose on satiety and plasma concentrations of glucose, insulin and ghrelin in healthy humans. Thirteen healthy (BMI: 23.2±3.3) participants (6 men, 7 women) aged 21‐40 y fasted overnight (10 hours) then consumed isocaloric beverages (240 kcal) sweetened with sucrose, clover honey, or glucose in a randomized, crossover design where glucose served as a control. Fingerprick blood samples were collected and satiety ratings were assessed prior to beverage consumption and 15, 30, 45, 60, 90 and 120 minutes following the start of ingestion. Plasma was analyzed for concentrations of glucose, insulin and ghrelin, and area under the curve (AUC) or over the curve was calculated for all variables. Satiety was not different between sucrose and honey. Lower (p<0.05) AUCs for plasma glucose were detected for honey (‐35±28%) and sucrose (‐27±29%) relative to glucose consumption. No differences in insulin or ghrelin responses were detected among groups. Honey promoted a potentially healthier response than glucose but not sucrose with regard to postprandial glucose metabolism, but no differences in the satiating effects of the sweeteners were detected. Supported by the American Heart Association.