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Effect of protein sources on glucose and insulin response in overweight and obese men
Author(s) -
Courville Amber Beverlie,
Stote Kim S,
Rumpler William V,
Paul David R,
Leger Jayme,
Novotny Janet A,
Baer David J
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.345.3
Subject(s) - lactose , maltodextrin , crossover study , whey protein , insulin , whey protein isolate , sucrose , food science , overweight , endocrinology , soy protein , medicine , chemistry , obesity , placebo , alternative medicine , organic chemistry , pathology , spray drying
Two randomized, double blinded, crossover designed studies were performed to examine the effect of whey protein on glucoregulation. In the first study, 15 healthy male subjects (age 43‐65, BMI 28‐38) consumed a shake containing whey protein concentrate (WPC‐80), soy protein isolate (SPI) or maltodextrin twice daily with their habitual diet. On the eighth day, fasted subjects underwent an oral glucose tolerance test. In the second study, 9 healthy male subjects (aged 47‐65, BMI 25‐31) were fasted for 12 hours before consuming a hot cereal containing sucrose + whey protein isolate (WPI), sucrose + SPI, lactose + WPI, or lactose + SPI. In both studies, glucose and insulin were measured every 30 minutes for 4 hours. Results of the first study showed no differences in glucose or insulin concentrations among treatments. However, in the second study when WPI was consumed with lactose, the area under the curve for glucose was lower than SPI consumed with lactose (24727 ± 475 vs. 25690 ± 475, p=0.02). Thus, the effect of dairy protein on glucoregulation may be due to the interaction of multiple nutrients.