Premium
Tomato Product Adherence Dynamics in African‐American Men at Risk for Prostate Cancer
Author(s) -
Park Eunyoung,
StacewiczSapuntzakis Maria,
Sharifi Roohollah,
Freeman Vincent,
Xie Hui,
Tampe Carolyn,
Bowen Phyllis E.
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.34.1
Subject(s) - lycopene , medicine , prostate cancer , psychological intervention , incidence (geometry) , endocrinology , cancer , biology , food science , carotenoid , nursing , physics , optics
African‐American (AA) men have the highest incidence of prostate cancer (PC) and tomato product (TP) intake is associated with reduced risk. Can AA men significantly increase self‐selected TP intake through diet counseling alone? AA men with PSA ≥ 2.5 ng/mL were randomized to either increase TP intake (intervention group (IG), N = 22) through weekly telephone calls, or to a control group (CG, N=14) receiving no TP coaching over 3 months. Mean dietary lycopene intake was 24.6 ± 27.1 and 5.8 ± 9.6 mg/d, respectively for IG and CG (p = 0.04). The IG consumed a mean of 7.1 TP servings/wk and CG only 3.5 (p = 0.005). The IG increased plasma lycopene level by 53% and 40%, at 1 and 3 months (p = 0.001, p = 0.003, respectively), while there was no increase in the CG. Subjects with high baseline leukocyte DNA damage had significantly less damage after 3 months (22.8%). Incentives/impediments to TP intake were assessed weekly in the IG. Incentives in order of frequency were (1) in study, (2) likability, (3) mass media, (4) social support. Impediments were (1) forgot, (2) run out, (3) hospitalization/sick, (4) tight budget. AA men at risk for PC were able and willing to increase TP intake sufficiently to raise plasma lycopene levels and decrease DNA damage over 3 months. Self‐selected whole food interventions through diet counseling alone may be a feasible approach for efficacy studies. Support: Roybal Center Health Promotion, UIC