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Anti‐inflammatory Actions of Oat Beta Glucans in an Exercise Stress Model
Author(s) -
DiSilvestro Robert A,
Creamer Jennifer
Publication year - 2009
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.23.1_supplement.221.8
Subject(s) - inflammation , medicine , placebo , malondialdehyde , endocrinology , myeloperoxidase , oxidative stress , pathology , alternative medicine
Beta glucans are dietary fiber but some goes intact into circulation. This could generate systemic anti‐inflammatory actions. In young adult men, beta glucans (3 g/d, 4 wk) as oat bran (Oatvantage(tm)) decreased exercise‐induced inflammation based on soreness perception. The result was not duplicated by a low fiber placebo. Inflammation was induced by a single leg extension protocol done before and after the 4 wk intervention. Soreness in the beta glucan group fell by 1.4 on a 10 point scale from pre‐ to post‐intervention, while the placebo group's soreness rose by 0.4. In addition, serum myeloperoxidase, a marker of inflammation, rose significantly after exercise pre‐intervention in the beta glucan group, but not at post‐intervention. Beta glucans intake also decreased an exercise effect on serum malondialdehyde, a marker of oxidant stress that can be associated with inflammation. These results show that beta glucans can blunt lipid peroxidation and inflammation caused by exercise, while decreasing soreness post‐exercise. Further work should be done to see if beta glucans can exert other anti‐inflammatory effects, including those relevant to cardiovascular disease.