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Relationship between body mass index and cardiovascular risk factors in osteopenic postmenopausal women
Author(s) -
Chai Sheau C,
Saadat Raz L,
Hooshmand Shirin,
Arjmandi Bahram H
Publication year - 2008
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.22.2_supplement.800
Subject(s) - overweight , medicine , body mass index , endocrinology , obesity , diabetes mellitus , cholesterol , risk factor
Obese individuals hold an increased risk of several chronic and degenerative diseases including cardiovascular disease (CVD) and diabetes. The present study examined the relationship between body mass index (BMI; kg/m 2 ) and indices of CVD risk factors including lipid profiles and fasting blood glucose levels in osteopenic postmenopausal women. One hundred and twenty‐two (122) osteopenic, otherwise healthy postmenopausal women were divided into three groups based on their BMI values: 1) normal (18.5–24.9); 2) overweight (25–29.9); and 3) obese (>30). BMI was positively correlated with glucose (r=0.246), triglycerides (r=0.343), and Apo‐B (r=0.224), while negatively correlated with serum HDL‐cholesterol (r=‐0.384) and Apo‐A1 (r=‐0.257). In addition, overweight and obese individuals had lower serum levels of HDL‐cholesterol and Apo‐A1 and higher levels of triglycerides compared to individuals with normal BMI. Obese and overweight individuals also had somewhat higher serum total cholesterol and LDL‐cholesterol concentrations in comparison with individuals with normal BMI. Mean glucose levels were significantly increased as BMI values increased. The significance of these data is two‐fold: 1) contrary to general notion, overweight and obese individuals do experience bone loss, and 2) BMI values can be used as predictor of CVD risk factors.